Xylaria hypoxylon is a species of bioluminescentfungus in the family Xylariaceae. It is known by a variety of common names, such as the candlestick fungus, the candlesnuff fungus, carbon antlers,[1] or the stag's horn fungus.[2] The fruit bodies, characterized by erect, elongated black branches with whitened tips, typically grow in clusters on decaying hardwood. The fungus can cause a root rot in hawthorn and gooseberry plants.[3]
Xylaria hypoxylon was first described by Carl Linnaeus in 1745,[4] and then later mentioned by him in his Species Plantarum II.[5]
The specific epithet is derived from the Greek words hypo meaning "below", and xylon, meaning "wood".
Genetic evidence has created the Xylaria hypoxylon complex. The complex was created when taxonomists and amateurs noticed large variation in appearance and spore shape within the main species and decided that the differences were large enough to warrant a complex formation. This complex has been debated between different experts as valid and invalid for the past three years and has remained in tension.[6][7][8]
Fruit bodies (ascocarps) are cylindrical or flattened with dimensions of 3–8 centimetres (1+1⁄8–3+1⁄8in) tall × 2–8 mm thick.[1] The erect ascocarps are often twisted or bent, and typically sparsely branched, often in a shape resembling a stag's antlers. Specimens found earlier in the season, in spring, may be covered completely in asexual spores (conidia), which manifests itself as a white to grayish powdery deposit. Later in the season, mature ascocarps are charcoal-black, and have minute pimple-like bumps called perithecia on the surface. These are minute rounded spore bearing structures with tiny holes, or ostioles, for the release of sexual spores (ascospores). The perithecia are embedded in the flesh of the ascocarp, the stroma, which is tough, elastic, and white. Within the perithecia, the asci are 100 × 8 μm.[9]
Ascospores are kidney-shaped, black, and smooth, with dimensions of 10–14 × 4–6 μm.[10] The asexual spores (mitospores) are ellipsoid in shape, smooth, and hyaline.[11]
A variety of chemical compounds with in vitro properties have been identified in this fungus. The compounds xylarial A and B both have moderate cytotoxic activity against the human hepatocellular carcinoma cell line Hep G2.[14] The pyrone derivative compounds named xylarone and 8,9-dehydroxylarone also have cytotoxic activity.[15] Several cytochalasins, compounds that bind to actin in muscle tissue, have been found in the fungus.[16]X. hypoxylon also contains a carbohydrate-binding protein, a lectin, with a unique sugar specificity, and which has potent anti-tumor effects in various tumor cell lines.[17]
^ abSundberg W, Bessette A (1987). Mushrooms: A Quick Reference Guide to Mushrooms of North America (Macmillan Field Guides). New York: Collier Books. p. 10. ISBN0-02-063690-3.
^Linnaeus C. (1745). Flora svecica [suecica] exhibens plantas per regnum Sueciae crescentes. Vol. 2. Stockholm: Salvii.
^Linnaeus C. (1753). Species Plantarum, exhibentes plantas rites cognitus ad genera relatas cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas. Vol. II. Stockholm: Salvii.
^Espada A, Rivera Sagredo A, de la Fuente JM, Hueso Rodriguez JA, Elson SW. (1997). "New cytochalasins from the fungus Xylaria hypoxylon." Tetrahedron53(18): 6485–92.
^Liu Q, Wang H, Ng TB (2006). "First report of a xylose-specific lectin with potent hemagglutinating, antiproliferative and anti-mitogenic activities from a wild ascomycete mushroom". Biochim. Biophys. Acta. 1760 (12): 1914–9. doi:10.1016/j.bbagen.2006.07.010. PMID16952421.
