Cannon's first professional comics work was The Chainsaw Vigilante, a spin-off from The Tick, from New England Comics. Beginning in the mid-1990s, he wrote and drew The Replacement God, a fantasy comic book about a former slave named Knute who is pursued across the fictional land of Mun by a tyrannical king and his beatnik Visigoth Death Horde. The first eight issues were published by Slave Labor Graphics, a subsequent five issues were published by Image Comics, and one issue was self-published by Cannon under his Handicraft Guild imprint.
Cannon worked as layout artist on Top 10, with writer Alan Moore and finishing artist Gene Ha, and pencilled its spin-off miniseries Smax, with Moore and inker Andrew Currie, for America's Best Comics. Cannon won a joint Eisner for Best Continuing Series in 2001 for his work on Top 10.
Zander and Kevin Cannon have worked together on many comics & illustration projects, including several nonfiction graphic novels. In 2012 they launched the digital comics magazine Double Barrel, in which Zander Cannon is serializing the graphic novel Heck, his first long-form solo comics project since The Replacement God. Top Shelf Productions collected Heck into graphic novel format in 2013.[1] "Heck" was nominated for an Eisner for『Best Graphic Album—Reprint』in 2014 but did not win.[2]
Cannon has been developing the Kaijumax series since 2015 as writer and artist. Kaijumax tells the story of a kaiju (monster in Japanese) jail.
