| Zincke nitration | |
|---|---|
| Named after | Theodor Zincke |
| Reaction type | Substitution reaction |
| Identifiers | |
| RSC ontology ID | RXNO:0000413 |
The Zincke nitration is a nitration reaction in which a bromine is replaced by a nitro group on an electron-rich aryl compound such as a phenolorcresol. Typical reagents are nitrous acidorsodium nitrite. The reaction is a manifestation of nucleophilic aromatic substitution and is named after Theodor Zincke, who first reported it in 1900.[1][2]
Two examples:[3]
and:[4]
The Zincke nitration should not be confused with the Zincke–Suhl reaction or the Zincke reaction.
