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受容体逆作動薬

出典: フリー百科事典『ウィキペディア(Wikipedia)』
完全作動薬(Fa)、部分作動薬(Pa)、遮断薬(Na)、逆作動薬(Ia)の用量反応曲線

inverse agonist[1]

intrinsic activity 

100%0%0%

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GABAAGABAARo15-4513β-[2][3]

AgRPASIP.4Mc4R1Mc1R[4]

μ

関連資料[編集]

  • “Inverse agonism and its therapeutic significance”. Indian Journal of Pharmacology 43 (5): 492–501. (September 2011). doi:10.4103/0253-7613.84947. PMC 3195115. PMID 22021988. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195115/. 

脚注[編集]

  1. ^ “Principles: receptor theory in pharmacology”. Trends in Pharmacological Sciences 25 (4): 186–92. (April 2004). doi:10.1016/j.tips.2004.02.012. PMID 15063082. 
  2. ^ “Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves gamma-aminobutyric acidA-gated chloride channels”. The Journal of Pharmacology and Experimental Therapeutics 246 (2): 558–64. (August 1988). PMID 2457076. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=2457076. 
  3. ^ “Pharmacology of benzodiazepine receptors: an update”. Journal of Psychiatry & Neuroscience 19 (1): 24–9. (January 1994). PMC 1188559. PMID 8148363. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188559/. 
  4. ^ “Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo”. Genes & Development 12 (3): 316–30. (February 1998). doi:10.1101/gad.12.3.316. PMC 316484. PMID 9450927. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316484/. 

関連項目[編集]

外部リンク[編集]