Testis-specific basic protein Y 2 also known as basic charge, Y-linked 2 is a protein that in humans is encoded by the BPY2 gene which resides on the Y chromosome.[3]
BPY2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | BPY2, BPY2A, VCY2, VCY2A, basic charge, Y-linked, 2, basic charge Y-linked 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 400013; GeneCards: BPY2; OMA:BPY2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein interacts with ubiquitin protein ligase E3A and may be involved in male germ cell development and male infertility. Three nearly identical copies of this gene exist on chromosome Y; two copies are part of a palindromic region. This record represents the copy outside of the palindromic region.[4]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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