● Home ● Random ● Nearby ● Log in ● Settings ● Donate ● About Wikipedia ● Disclaimers

STRBP

● Article ● Talk ● Language ● Watch ● Edit

Spermatid perinuclear RNA-binding protein is a protein that in humans is encoded by the STRBP gene.^[5]

STRBP

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2DMY

Identifiers

STRBP, HEL162, ILF3L, SPNR, p74, spermatid perinuclear RNA binding protein

External IDs

OMIM: 611138; MGI: 104626; HomoloGene: 7548; GeneCards: STRBP; OMA:STRBP - orthologs

Gene location (Human)

Chr.	Chromosome 9 (human)^[1]

Band	9q33.3	Start	123,109,500 bp^[1]
Band	9q33.3	End	123,268,586 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 2 (mouse)^[2]

Band	2\|2 B	Start	37,373,240 bp^[2]
Band	2\|2 B	End	37,593,871 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

secondary oocyte

primary visual cortex

lateral nuclear group of thalamus

Brodmann area 23

sperm

ganglionic eminence

endothelial cell

parietal lobe

postcentral gyrus

epithelium of nasopharynx

Top expressed in

tail of embryo

lacrimal gland

genital tubercle

zygote

medial dorsal nucleus

olfactory epithelium

Rostral migratory stream

medial geniculate nucleus

spermatocyte

secondary oocyte

More reference expression data

n/a

Gene ontology
Molecular function	DNA binding double-stranded RNA binding protein binding single-stranded RNA binding RNA binding microtubule binding tubulin binding
Cellular component	cytoplasm microtubule cytoskeleton nucleus manchette
Biological process	multicellular organism development mechanosensory behavior cell differentiation spermatogenesis spermatid development
Sources:Amigo / QuickGO

Species

Human

Mouse


55342


20744


ENSG00000165209


ENSMUSG00000026915


Q96SI9


Q91WM1

RefSeq (mRNA)


NM_001171137 NM_018387 NM_001376106 NM_001376107 NM_001376109

NM_009261 NM_176932 NM_001355259 NM_001379314 NM_001379315
NM_001379316

RefSeq (protein)


NP_001164608 NP_060857 NP_001363035 NP_001363036 NP_001363038


NP_033287 NP_001342188 NP_001366243 NP_001366244 NP_001366245

Location (UCSC)

Chr 9: 123.11 – 123.27 Mb

Chr 2: 37.37 – 37.59 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165209 – Ensembl, May 2017

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026915 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Entrez Gene: STRBP spermatid perinuclear RNA binding protein".

Further reading

Schumacher JM, Lee K, Edelhoff S, Braun RE (May 1995). "Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules". The Journal of Cell Biology. 129 (4): 1023–32. doi:10.1083/jcb.129.4.1023. PMC 2120489. PMID 7744952.

Schumacher JM, Artzt K, Braun RE (July 1998). "Spermatid perinuclear ribonucleic acid-binding protein binds microtubules in vitro and associates with abnormal manchettes in vivo in mice". Biology of Reproduction. 59 (1): 69–76. doi:10.1095/biolreprod59.1.69. PMID 9674995.

Coolidge CJ, Patton JG (March 2000). "A new double-stranded RNA-binding protein that interacts with PKR". Nucleic Acids Research. 28 (6): 1407–17. doi:10.1093/nar/28.6.1407. PMC 111047. PMID 10684936.

Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.

Pires-daSilva A, Nayernia K, Engel W, Torres M, Stoykova A, Chowdhury K, Gruss P (May 2001). "Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities" (PDF). Developmental Biology. 233 (2): 319–28. doi:10.1006/dbio.2001.0169. hdl:11858/00-001M-0000-0012-F717-7. PMID 11336498.

Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.

Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

t

e

Retrieved from "https://en.wikipedia.org/w/index.php?title=STRBP&oldid=1115898602" Last edited on 13 October 2022, at 19:48

Languages

●العربية ●Bosanski ●Español ●مصرى ●Татарча / tatarça ●Українська

●This page was last edited on 13 October 2022, at 19:48 (UTC). ●Content is available under CC BY-SA 4.0 unless otherwise noted. ●Privacy policy ●About Wikipedia ●Disclaimers ●Contact Wikipedia ●Code of Conduct ●Developers ●Statistics ●Cookie statement ●Terms of Use ●Desktop