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Latest revision Your text
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It is biodegraded by both aerobic and anaerobic bacteria to 3,6-[[dichlorosalicylic acid]]. This conversion is catalyzed by a [[Dioxygenase|dicamba monooxygenase]], which hydroxylates the methyl group of dicamba. The hydroxymethylated derivative hydrolyzes readily to an inactive dichlorosalicylic acid or its [[conjugate base]]. Modification of the gene encoding this enzyme is one strategy toward dicamba-resistant crops.<ref>{{cite journal |doi=10.1016/j.jmb.2009.07.021 |title=Crystal Structure of Dicamba Monooxygenase: A Rieske Nonheme Oxygenase that Catalyzes Oxidative Demethylation |date=2009 |last1=Dumitru |first1=Razvan |last2=Jiang |first2=Wen Zhi |last3=Weeks |first3=Donald P. |last4=Wilson |first4=Mark A. |journal=Journal of Molecular Biology |volume=392 |issue=2 |pages=498–510 |pmid=19616011 |pmc=3109874 }}</ref> The dichlorosalicylic acid is far less toxic than dicamba, which is already rather low.<ref>{{cite journal | last1=Krueger | first1=James P. | last2=Butz | first2=Robert G. | last3=Atallah | first3=Yousef H. | last4=Cork | first4=Douglas J. | title=Isolation and identification of microorganisms for the degradation of Dicamba | journal=Journal of Agricultural and Food Chemistry | volume=37 | issue=2 | date=1989 | issn=0021-8561 | doi=10.1021/jf00086a057 | pages=534–538}}</ref><ref>{{cite journal | last1=Milligan | first1=Peter W. | last2=Häggblom | first2=Max M. | title=Biodegradation and Biotransformation of Dicamba under Different Reducing Conditions | journal=Environmental Science & Technology | volume=33 | issue=8 | date=1999-04-01 | issn=0013-936X | doi=10.1021/es981117e | pages=1224–1229| bibcode=1999EnST...33.1224M }}</ref>

It is biodegraded by both aerobic and anaerobic bacteria to 3,6-[[dichlorosalicylic acid]]. This conversion is catalyzed by a [[Dioxygenase|dicamba monooxygenase]], which hydroxylates the methyl group of dicamba. The hydroxymethylated derivative hydrolyzes readily to an inactive dichlorosalicylic acid or its [[conjugate base]]. Modification of the gene encoding this enzyme is one strategy toward dicamba-resistant crops.<ref>{{cite journal |doi=10.1016/j.jmb.2009.07.021 |title=Crystal Structure of Dicamba Monooxygenase: A Rieske Nonheme Oxygenase that Catalyzes Oxidative Demethylation |date=2009 |last1=Dumitru |first1=Razvan |last2=Jiang |first2=Wen Zhi |last3=Weeks |first3=Donald P. |last4=Wilson |first4=Mark A. |journal=Journal of Molecular Biology |volume=392 |issue=2 |pages=498–510 |pmid=19616011 |pmc=3109874 }}</ref> The dichlorosalicylic acid is far less toxic than dicamba, which is already rather low.<ref>{{cite journal | last1=Krueger | first1=James P. | last2=Butz | first2=Robert G. | last3=Atallah | first3=Yousef H. | last4=Cork | first4=Douglas J. | title=Isolation and identification of microorganisms for the degradation of Dicamba | journal=Journal of Agricultural and Food Chemistry | volume=37 | issue=2 | date=1989 | issn=0021-8561 | doi=10.1021/jf00086a057 | pages=534–538}}</ref><ref>{{cite journal | last1=Milligan | first1=Peter W. | last2=Häggblom | first2=Max M. | title=Biodegradation and Biotransformation of Dicamba under Different Reducing Conditions | journal=Environmental Science & Technology | volume=33 | issue=8 | date=1999-04-01 | issn=0013-936X | doi=10.1021/es981117e | pages=1224–1229| bibcode=1999EnST...33.1224M }}</ref>



== Use on dicamba-tolerant crops ==

== Dicamba use on dicamba-tolerant crops ==

Complaints against dicamba accelerated after the United States EPA approved a Monsanto-created soybean which could tolerate it in 2016.<ref name="dicambadestroy">{{Cite web |title=Dicamba Lawsuit &#124; Crop Damage Compensation for Farmers |url=https://www.consumernotice.org/legal/dicamba-lawsuits/ |website=ConsumerNotice.org}}</ref> The soybean was a part of Monsanto's Xtend products.<ref name="dicambadestroy" /> Dicamba was approved by the EPA for "over-the-top" (OTT) use on those dicamba-tolerant soybean and cotton crops.<ref name=":0" /> In 2017 and again in 2018, EPA amended the registrations of all OTT dicamba products following reports that farmers had experienced crop damage and economic losses resulting from spray drifting.<ref name=":0" />

Complaints against dicamba accelerated after the United States EPA approved a Monsanto-created soybean which could tolerate it in 2016.<ref name="dicambadestroy">{{Cite web |title=Dicamba Lawsuit &#124; Crop Damage Compensation for Farmers |url=https://www.consumernotice.org/legal/dicamba-lawsuits/ |website=ConsumerNotice.org}}</ref> The soybean was a part of Monsanto's Xtend products.<ref name="dicambadestroy" /> Dicamba was approved by the EPA for "over-the-top" (OTT) use on those dicamba-tolerant soybean and cotton crops.<ref name=":0" /> In 2017 and again in 2018, EPA amended the registrations of all OTT dicamba products following reports that farmers had experienced crop damage and economic losses resulting from spray drifting.<ref name=":0" />



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