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Tromantadine

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Tromantadine
Clinical data
File:Tromantadine.png
Routes of administration	Topical
ATC code	D06BB02 (WHO)
Identifiers
IUPAC name N-1-adamantyl-N-[2-(dimethylamino)ethoxy]acetamide
CAS Number	53783-83-8
PubChem CID	64377
CompTox Dashboard (EPA)	DTXSID00202062
ECHA InfoCard	100.053.409
Chemical and physical data
Formula	C₁₆H₂₈N₂O₂
Molar mass	280.406 g/mol g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(C)N(OCCN(C)C)C23CC1CC(C3)CC(C2)C1

Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade name Viru-Merz®. Its performance is similar to aciclovir.

Tromantadine inhibits the early and late events in the virus replication cycle. It changes the glycoproteins of the host cells, therefore impeding the absorption of the virus. It inhibits penetration of the virus. It also prevents uncoating of the virions.

Like rimantadine and amantadine, tromantadine is a derivate of adamantane.

See also [1]