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1 References  













2-Methyl-MDA






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From Wikipedia, the free encyclopedia
  

2-Methyl-MDA
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
Identifiers

  • 1-(4-methyl-1,3-benzodioxol-5-yl)propan-2-amine

CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H15NO2
Molar mass193.246 g·mol−1
3D model (JSmol)

  • O2COc1c2ccc(c1C)CC(C)N

  • InChI=1S/C11H15NO2/c1-7(12)5-9-3-4-10-11(8(9)2)14-6-13-10/h3-4,7H,5-6,12H2,1-2H3 checkY

  • Key:WVACHJAKQMSYSU-UHFFFAOYSA-N checkY

 ☒NcheckY (what is this?)  (verify)

2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen[citation needed] and psychedelic[citation needed] drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux.[1] 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA.[1] However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA.[1]

References[edit]

  1. ^ a b c Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE (March 1998). "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry. 41 (6): 1001–5. CiteSeerX 10.1.1.688.9559. doi:10.1021/jm9705925. PMID 9526575.


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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=2-Methyl-MDA&oldid=1206224514"
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