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Find sources: "Acediasulfone" – news · newspapers · books · scholar · JSTOR (March 2024) |
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ECHA InfoCard | 100.001.131 |
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Formula | C14H14N2O4S |
Molar mass | 306.34 g·mol−1 |
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Acediasulfone (INN) is an antimicrobial drug, which also has antimalarial activity. It is a long-acting prodrugofdapsone, which is used for treating leprosy.
Dapsone is somewhat inconvenient to administer to patients because of its rather low water solubility.
In the search for more easily administered drugs, dapsone (1) was reacted with bromoacetic acid to give acediasulfone (2) which can be administered as a water-soluble salt.
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