Contents

CENPT

Centromere- and microtubule-associated protein

CENPT
Identifiers
Aliases	CENPT, C16orf56, CENP-T, centromere protein T, SSMGA
External IDs	OMIM: 611510; MGI: 2443939; HomoloGene: 41610; GeneCards: CENPT; OMA:CENPT - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q22.1 Start 67,828,157 bp[1] End 67,847,811 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 D3 Start 106,571,305 bp[2] End 106,579,910 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right testis left testis skin of abdomen skin of leg granulocyte right ovary left ovary body of pancreas muscle layer of sigmoid colon Top expressed in yolk sac endocardial cushion internal carotid artery external carotid artery otic vesicle endothelial cell of lymphatic vessel ventricular zone morula blastocyst maxillary prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein heterodimerization activity protein binding DNA binding histone binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytosol chromosome nucleoplasm chromosome, centromeric region nucleus kinetochore nuclear body Biological process kinetochore assembly CENP-A containing chromatin assembly chromosome organization chromosome segregation cell division cell cycle protein localization to kinetochore involved in kinetochore assembly mitotic cell cycle regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80152 320394 Ensembl ENSG00000102901 ENSMUSG00000036672 UniProt Q96BT3 Q3TJM4 RefSeq (mRNA) NM_025082 NM_177150 RefSeq (protein) NP_079358 NP_796124 Location (UCSC) Chr 16: 67.83 – 67.85 Mb Chr 8: 106.57 – 106.58 Mb PubMed search [3] [4]
Wikidata
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Centromere protein T is a protein that in humans is encoded by the CENPT gene.^[5][6][7]

Mutations in CENPT cause an autosomal recessive syndrome of microcephaly, short stature, skeletal abnormalities, underdeveloped genitalia and pubertal delay.^[8]

• CENPE
• CENPF
• CENPJ

• Human CENPT genome location and CENPT gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.