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CHD9

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CHD9

Identifiers

Aliases

CHD9, AD013, CReMM, KISH2, PRIC320, CHD-9, chromodomain helicase DNA binding protein 9

External IDs

OMIM: 616936; MGI: 1924001; HomoloGene: 11844; GeneCards: CHD9; OMA:CHD9 - orthologs

Gene location (Human)

Chr.	Chromosome 16 (human)^[1]

Band	16q12.2	Start	53,054,991 bp^[1]
Band	16q12.2	End	53,329,150 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 8 (mouse)^[2]

Band	8\|8 C4	Start	91,554,980 bp^[2]
Band	8\|8 C4	End	91,781,144 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

Achilles tendon

tibia

mucosa of paranasal sinus

tendon of biceps brachii

skin of hip

visceral pleura

renal medulla

urethra

pylorus

corpus callosum

Top expressed in

right kidney

esophagus

lip

hand

aortic valve

zygote

ascending aorta

otolith organ

utricle

secondary oocyte

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	DNA binding nucleotide binding hydrolase activity, acting on acid anhydrides protein binding ATP binding hydrolase activity helicase activity
Cellular component	nucleoplasm nucleus cytoplasm
Biological process	regulation of transcription, DNA-templated transcription, DNA-templated regulation of lipid metabolic process chromatin organization
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


80205


109151

Ensembl


ENSG00000177200


ENSMUSG00000056608

UniProt


Q3L8U1


Q8BYH8

RefSeq (mRNA)

NM_001308319 NM_015287 NM_025134 NM_001352127 NM_001352156
NM_001352157 NM_001352158 NM_001382353 NM_001382354 NM_001382355


NM_177224 NM_001310530

RefSeq (protein)

NP_001295248 NP_079410 NP_001339056 NP_001339085 NP_001339086
NP_001339087 NP_001369282 NP_001369283 NP_001369284


NP_001297459 NP_796198

Location (UCSC)

Chr 16: 53.05 – 53.33 Mb

Chr 8: 91.55 – 91.78 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Chromodomain-helicase-DNA-binding protein 9 is an enzyme that in humans is encoded by the CHD9 gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000177200 – Ensembl, May 2017

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056608 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" (PDF). DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.

^ "Entrez Gene: CHD9 chromodomain helicase DNA binding protein 9".

External links[edit]

Human CHD9 genome location and CHD9 gene details page in the UCSC Genome Browser.

Further reading[edit]

Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (Aug 2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.

Shur I, Benayahu D (Sep 2005). "Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein". Journal of Molecular Biology. 352 (3): 646–55. doi:10.1016/j.jmb.2005.06.049. PMID 16095617.

Marom R, Shur I, Hager GL, Benayahu D (Jun 2006). "Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors". Journal of Cellular Physiology. 207 (3): 628–35. doi:10.1002/jcp.20611. PMID 16523501. S2CID 21524910.

Surapureddi S, Viswakarma N, Yu S, Guo D, Rao MS, Reddy JK (May 2006). "PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex". Biochemical and Biophysical Research Communications. 343 (2): 535–43. doi:10.1016/j.bbrc.2006.02.160. PMID 16554032.

Shur I, Solomon R, Benayahu D (May 2006). "Dynamic interactions of chromatin-related mesenchymal modulator, a chromodomain helicase-DNA-binding protein, with promoters in osteoprogenitors". Stem Cells. 24 (5): 1288–93. doi:10.1634/stemcells.2005-0300. PMID 16705189. S2CID 24621014.

Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

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