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1 References  














CS-27349







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CS-27349
Identifiers
  • (1R,2R,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-2-yl hydroxy(diphenyl)acetate

CAS Number
  • HCl64520-33-8
  • PubChem CID
  • HCl: 3049184
  • ChemSpider
  • HCl: 57264798
  • ChEMBL
    CompTox Dashboard (EPA)
  • HCl: DTXSID90983151
  • Chemical and physical data
    FormulaC22H25NO3
    Molar mass351.446 g·mol−1
    3D model (JSmol)
    • CN1C2CC[C@H](C1CC2)OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl

    • InChI=1S/C22H25NO3/c1-23-18-12-14-19(23)20(15-13-18)26-21(24)22(25,16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-20,25H,12-15H2,1H3/t18?,19?,20-/m1/s1

    • Key:LSJGAYNIIMEDLR-SOAGJPPSSA-N

    CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonisttomuscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ.[1] It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.[2]

    References[edit]

    1. ^ Ball JC (2015). "Dual Use Research of Concern: Derivatives of 3-Quinuclidinyl Benzilate". Military Medical Science Letters. 84 (1): 2–41. doi:10.31482/mmsl.2015.001.
  • ^ Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances (PDF) (Report). Ho-Chunk Technical Solutions Healthcare Division. February 29, 2016. Archived (PDF) from the original on December 25, 2020.

  • t
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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=CS-27349&oldid=1207396995"

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    This page was last edited on 14 February 2024, at 18:37 (UTC).

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