chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | |||||||
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Identifiers | |||||||
Symbol | CXCL6 | ||||||
Alt. symbols | SCYB6, GCP-2, CKA-3 | ||||||
NCBI gene | 6372 | ||||||
HGNC | 10643 | ||||||
OMIM | 138965 | ||||||
RefSeq | NM_002993 | ||||||
UniProt | P80162 | ||||||
Other data | |||||||
Locus | Chr. 4 q21 | ||||||
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Chemokine (C-X-C motif) ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family that is also known as granulocyte chemotactic protein 2 (GCP-2). As its former name suggests, CXCL6 is a chemoattractant for neutrophilic granulocytes.[5][6] It elicits its chemotactic effects by interacting with the chemokine receptors CXCR1 and CXCR2.[6] The gene for CXCL6 is located on human chromosome 4 in a cluster with other CXC chemokine genes.[7][8]
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CXC |
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C (XC) |
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CX3C |
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Others |
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