Jump to content

Main menu Navigation ●Main page ●Contents ●Current events ●Random article ●About Wikipedia ●Contact us ●Donate Contribute ●Help ●Learn to edit ●Community portal ●Recent changes ●Upload file

●Create account ●Log in ●Create account ● Log in Pages for logged out editors learn more ●Contributions ●Talk

(Top) 1 References

Dimaprit

●تۆرکجه ●فارسی ●Српски / srpski ●Srpskohrvatski / српскохрватски Edit links ●Article ●Talk ●Read ●Edit ●View history Tools Actions ●Read ●Edit ●View history General ●What links here ●Related changes ●Upload file ●Special pages ●Permanent link ●Page information ●Cite this page ●Get shortened URL ●Download QR code ●Wikidata item Print/export ●Download as PDF ●Printable version In other projects ●Wikimedia Commons Appearance From Wikipedia, the free encyclopedia

Dimaprit
Names

Preferred IUPAC name 3-(Dimethylamino)propyl carbamimidothioate
Other names 3-dimethylaminopropyl sulfanylmethanimidamide
Identifiers
CAS Number	65119-89-3^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL12344^N
ChemSpider	2968^N
IUPHAR/BPS	1248
KEGG	C17930^N
PubChem CID	3077
UNII	ZZQ699148P^N
CompTox Dashboard (EPA)	DTXSID0037154
InChI InChI=1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)^N Key: OLHQOJYVQUNWPL-UHFFFAOYSA-N^N InChI=1/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8) Key: OLHQOJYVQUNWPL-UHFFFAOYAQ
SMILES CN(C)CCCSC(=N)N
Properties
Chemical formula	C₆H₁₅N₃S
Molar mass	161.2684 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Dimaprit is a histamine analog working as a selective H₂ histamine receptor agonist.^[1]^[2]^[3]

References[edit]

^ Kartzung, Betram G.; Trevor, Anthony J., eds. (2014). Basic and Clinical Pharmacology (13th ed.). New York: McGraw-Hill Education. p. 364. ISBN 978-0071825054.

^ Kohno, S; Ogawa, K; Nabe, T; Yamamura, H; Ohata, K (May 1993). "Dimaprit, a Histamine H₂-agonist, Inhibits Anaphylactic Histamine Release from Mast Cells and the Decreased Release is Restored by Thioperamide (H₃-antagonist), but not by Cimetidine (H₂-antagonist)". Japanese Journal of Pharmacology. 62 (1): 75–9. doi:10.1254/jjp.62.75. PMID 7688057.

^ Nakamura, T; Ueno, Y; Goda, Y; Nakamura, A; Shinjo, K; Nagahisa, A (March 1997). "Efficacy of a Selective Histamine H₂ Receptor Agonist, Dimaprit, in Experimental Models of Endotoxin Shock and Hepatitis in Mice". European Journal of Pharmacology. 322 (1): 83–89. doi:10.1016/S0014-2999(96)00987-9. PMID 9088875.