EPH receptor A5 (ephrin type-A receptor 5) is a protein that in humans is encoded by the EPHA5 gene.[5][6][7]
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.[7]
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Angiopoietin |
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CNTF |
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EGF (ErbB) |
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FGF |
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HGF (c-Met) |
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IGF |
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LNGF (p75NTR) |
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PDGF |
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RET (GFL) |
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SCF (c-Kit) |
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TGFβ |
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Trk |
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VEGF |
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Others |
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