Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene.[5][6] The protein encoded by this gene belongs to the ETS family of transcription factors.[5] It has been found to play a key role in the development of inflammatory bowel disease.[7][8]
ETS2 has been shown to interact with:
ETS2 has been linked to a variety of diseases, including Takayasu's arteritis, inflammatory bowel disease, primary sclerosing cholangitis, and ankylosing spondylitis, all associated with a region on chromosome 21at21q22.[13]
PDB gallery
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1k78: Pax5(1-149)+Ets-1(331-440)+DNA
1k79: Ets-1(331-440)+GGAA duplex
1k7a: Ets-1(331-440)+GGAG duplex
2stt: SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, 25 STRUCTURES
2stw: SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, RESTRAINED REGULARIZED MEAN STRUCTURE
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