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(Top) 1 References 2 Further reading

FAM57B

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TLCD3B

Identifiers

Aliases

TLCD3B, FP1188, family with sequence similarity 57 member B, FAM57B, TLC domain ceramide synthase 3B, TLC domain containing 3B, CORD22

External IDs

OMIM: 615175; MGI: 1916202; HomoloGene: 69491; GeneCards: TLCD3B; OMA:TLCD3B - orthologs

Gene location (Human)

Chr.	Chromosome 16 (human)^[1]

Band	16p11.2	Start	30,024,427 bp^[1]
Band	16p11.2	End	30,052,978 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 7 (mouse)^[2]

Band	7\|7 F3	Start	126,396,840 bp^[2]
Band	7\|7 F3	End	126,429,391 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

left testis

right testis

right hemisphere of cerebellum

ganglionic eminence

vena cava

right frontal lobe

pons

cingulate gyrus

anterior cingulate cortex

prefrontal cortex

Top expressed in

neural layer of retina

Rostral migratory stream

deep cerebellar nuclei

retinal pigment epithelium

pontine nuclei

cerebellar vermis

lobe of cerebellum

medial vestibular nucleus

inferior colliculus

epithelium of lens

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	sphingosine N-acyltransferase activity
Cellular component	integral component of membrane Golgi membrane Golgi apparatus endoplasmic reticulum membrane endoplasmic reticulum membrane
Biological process	ceramide biosynthetic process negative regulation of fat cell differentiation lipid metabolism
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


83723


68952

Ensembl


ENSG00000149926


ENSMUSG00000058966

UniProt


Q71RH2


Q7TNV1

RefSeq (mRNA)


NM_031478 NM_001318504 NM_001352173


NM_001146347 NM_026884 NM_029978

RefSeq (protein)


NP_001305433 NP_113666 NP_001339102


NP_001139819 NP_081160 NP_084254

Location (UCSC)

Chr 16: 30.02 – 30.05 Mb

Chr 7: 126.4 – 126.43 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Protein FAM57B is a protein that in humans is encoded by the FAM57B gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000149926 – Ensembl, May 2017

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058966 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

^ "Entrez Gene: FAM57B family with sequence similarity 57, member B".

Further reading[edit]

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.

Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

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