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Contents

   



(Top)
  


1 Reactions  




2 See also  




3 References  













Homarylamine






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From Wikipedia, the free encyclopedia
  

Homarylamine
Clinical data
Other names1,3-benzodioxolyl-N-methyl-5-ethanamine;
3,4-methylenedioxy-N-methyl-2-phenylethylamine;
Norlobivine
Routes of
administration		Various
Legal status
Legal status
  • US-SCHEDULE I DRUG as Positional isomer of MDA
Identifiers

  • 2-(1,3-Benzodioxol-5-yl)-N-methylethanamine

CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H13NO2
Molar mass179.219 g·mol−1
3D model (JSmol)

  • CNCCC1=CC2=C(C=C1)OCO2

  • InChI=1S/C10H13NO2/c1-11-5-4-8-2-3-9-10(6-8)13-7-12-9/h2-3,6,11H,4-5,7H2,1H3

  • Key:OPJOMVMFYOUDPK-UHFFFAOYSA-N

  (verify)

Homarylamine (INN;[1] also known as 3,4-methylenedioxy-N-methylphenethylamine and MDMPEA) is an antitussive (anti-cough) drug[2] which was patented in 1956 by Merck & Co.,[3] but has never been used medically as such.

Chemically it is a substituted phenethylamine. It is the N-methylated analogofmethylenedioxyphenethylamine (MDPEA). It is a schedule I drug in the USA as a positional isomer of MDA.

Methylenedioxyphenethylamine (MDPEA) for comparison

Reactions

[edit]

Reaction of homoarylamine with formaldehyde gives hydrastinine.

See also

[edit]

References

[edit]
  1. ^ "International Non-Proprietary Names for Pharmaceutical Preparations" (PDF). Chronicle of the World Health Organization. 12 (3). 1958.
  • ^ Stefko PL, Denzel J, Hickey I (March 1961). "Experimental Investigation of Nine Antitussive Drugs". Journal of Pharmaceutical Sciences. 50 (3): 216–221. doi:10.1002/jps.2600500309.
  • ^ U.S. patent 2,820,739



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    ●This page was last edited on 15 April 2022, at 07:19 (UTC).
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