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Contents

   



(Top)
  


1 References  




2 Further reading  




3 External links  













Integrin alpha 8






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From Wikipedia, the free encyclopedia
  
(Redirected from ITGA8)
ITGA8
Identifiers
AliasesITGA8, integrin subunit alpha 8
External IDsOMIM: 604063; MGI: 109442; HomoloGene: 37396; GeneCards: ITGA8; OMA:ITGA8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

8516

241226

Ensembl

ENSG00000077943

ENSMUSG00000026768

UniProt

P53708

A2ARA8

RefSeq (mRNA)

NM_001291494
NM_003638

NM_001001309

RefSeq (protein)

NP_001278423
NP_003629

NP_001001309
NP_001395029
NP_001395030
NP_001395031

Location (UCSC)Chr 10: 15.51 – 15.72 MbChr 2: 12.11 – 12.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene.[5][6]


References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000077943 – Ensembl, May 2017
  • ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026768 – Ensembl, May 2017
  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Schnapp LM, Breuss JM, Ramos DM, Sheppard D, Pytela R (Jul 1995). "Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells". J Cell Sci. 108 (2): 537–44. doi:10.1242/jcs.108.2.537. PMID 7768999.
  • ^ "Entrez Gene: ITGA8 integrin, alpha 8".

    • Further reading

    [edit]
  • Denda S, Müller U, Crossin KL, et al. (1998). "Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C". Biochemistry. 37 (16): 5464–74. doi:10.1021/bi9727489. PMC 2710129. PMID 9548928.
  • Hartner A, Schöcklmann H, Pröls F, et al. (1999). "Alpha8 integrin in glomerular mesangial cells and in experimental glomerulonephritis". Kidney Int. 56 (4): 1468–80. doi:10.1046/j.1523-1755.1999.00662.x. PMID 10504498.
  • Littlewood Evans A, Müller U (2000). "Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1". Nat. Genet. 24 (4): 424–8. doi:10.1038/74286. PMID 10742111. S2CID 2316181.
  • Brandenberger R, Schmidt A, Linton J, et al. (2001). "Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney". J. Cell Biol. 154 (2): 447–58. doi:10.1083/jcb.200103069. PMC 2150762. PMID 11470831.
  • Ljubimov AV, Saghizadeh M, Pytela R, et al. (2001). "Increased expression of tenascin-C-binding epithelial integrins in human bullous keratopathy corneas". J. Histochem. Cytochem. 49 (11): 1341–50. doi:10.1177/002215540104901102. PMID 11668187.
  • Valerius MT, Patterson LT, Feng Y, Potter SS (2002). "Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney". Proc. Natl. Acad. Sci. U.S.A. 99 (12): 8090–5. Bibcode:2002PNAS...99.8090V. doi:10.1073/pnas.122229199. PMC 123025. PMID 12060755.
  • Lu M, Munger JS, Steadele M, et al. (2003). "Integrin alpha8beta1 mediates adhesion to LAP-TGFbeta1". J. Cell Sci. 115 (Pt 23): 4641–8. doi:10.1242/jcs.00145. PMID 12415008.
  • Bieritz B, Spessotto P, Colombatti A, et al. (2004). "Role of alpha8 integrin in mesangial cell adhesion, migration, and proliferation". Kidney Int. 64 (1): 119–27. doi:10.1046/j.1523-1755.2003.00057.x. PMID 12787402.
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
  • Ekwa-Ekoka C, Diaz GA, Carlson C, et al. (2005). "Genomic organization and sequence variation of the human integrin subunit alpha8 gene (ITGA8)". Matrix Biol. 23 (7): 487–96. doi:10.1016/j.matbio.2004.08.005. PMID 15579315.
  • Scherberich A, Tucker RP, Degen M, et al. (2005). "Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin-dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro". Oncogene. 24 (9): 1525–32. doi:10.1038/sj.onc.1208342. PMID 15592496.
    • [edit]


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