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1 Related terminology  





2 References  





3 External links  














Imino acid






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From Wikipedia, the free encyclopedia
 


1-Pyrroline-5-carboxylic acid, an N-substituted imino acid

Inorganic chemistry, an imino acid is any molecule that contains both imine (>C=NH) and carboxyl (-C(=O)-OH) functional groups.[1]

Imino group attached to carbon
The two functional groups that together define an imino acid

Imino acids are structurally related to amino acids, which have amino group instead of imine—a difference of single vs double-bond between nitrogen and carbon. The simplest example is dehydroglycine.

D-Amino acid oxidase is an enzyme that is able to convert amino acids into imino acids. Also the direct biosynthetic precursor to the amino acid proline is the imino acid (S)-Δ1-pyrroline-5-carboxylate (P5C).

Related terminology[edit]

proline

Secondary amino acids, amino acids containing a secondary amine group are sometimes named imino acids,[2][3] though this usage is obsolescent.[1] The only proteinogenic amino acid of this type is proline, although the related non-proteinogenic amino acids hydroxyproline[4][5][6] and pipecolic acid[7] have often been included in studies of this class of compounds.

The term imino acid is also the obsolete term for imidic acids, structures containing the -C(=NH)-OH group, and should not be used for them.[1]

References[edit]

  1. ^ a b c IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Imino acids". doi:10.1351/goldbook.I02959
  • ^ Proline at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  • ^ "III. Amino Acids". Oklahoma State University. Archived from the original on 2008-01-18. Retrieved 2015-01-03.
  • ^ Myhill, D.; Jackson, D.S. (1963). "Separation of proline and hydroxyproline using thin-layer chromatography". Analytical Biochemistry. 6 (2): 193–198. doi:10.1016/0003-2697(63)90110-6. PMID 14061301.
  • ^ Stout, E.R.; Fritz, G.J. (1966). "Role of Oxygen Fixation in Hydroxyproline Biosynthesis by Etiolated Seedlings". Plant Physiology. 41 (2): 197–202. doi:10.1104/pp.41.2.197. PMC 1086318. PMID 16656240.
  • ^ Blumenkrantz, N.; Asboe-Hansen, G. (1975). "An assay for hydroxyproline and proline on one sample and a simplified method for hydroxyproline". Analytical Biochemistry. 63 (2): 331–340. doi:10.1016/0003-2697(75)90354-1. PMID 1122021.
  • ^ Maruyama, S; Miyoshi, S; Nomura, G; Suzuki, M; Tanaka, H; Maeda, H (1993). "Specificity for various imino-acid-residues of a proline-specific dipeptidylcarboxypeptidase from a Streptomyces species". Biochim Biophys Acta. 1162 (1–2): 72–76. doi:10.1016/0167-4838(93)90129-f. PMID 8448197.
  • External links[edit]


    Retrieved from "https://en.wikipedia.org/w/index.php?title=Imino_acid&oldid=1179446242"

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