Contents

KCNK12

Protein-coding gene in the species Homo sapiens

KCNK12
Identifiers
Aliases	KCNK12, K2p12.1, THIK-2, THIK2, potassium two pore domain channel subfamily K member 12
External IDs	OMIM: 607366; MGI: 2684043; HomoloGene: 11107; GeneCards: KCNK12; OMA:KCNK12 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p16.3 Start 47,509,290 bp[1] End 47,570,985 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 E4 Start 88,053,229 bp[2] End 88,105,422 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory bulb trigeminal ganglion spinal ganglia inferior olivary nucleus cerebellum cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum sural nerve primary visual cortex Top expressed in primary visual cortex cerebellar cortex superior frontal gyrus embryo granulocyte dentate gyrus of hippocampal formation granule cell neural layer of retina anterior horn of spinal cord olfactory bulb hippocampus proper More reference expression data BioGPS n/a
Gene ontology Molecular function potassium channel activity voltage-gated ion channel activity potassium ion leak channel activity Cellular component integral component of membrane membrane integral component of plasma membrane Biological process potassium ion transport regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56660 210741 Ensembl ENSG00000184261 ENSMUSG00000050138 UniProt Q9HB15 Q76M80 RefSeq (mRNA) NM_022055 NM_199251 RefSeq (protein) NP_071338 NP_954859 Location (UCSC) Chr 2: 47.51 – 47.57 Mb Chr 17: 88.05 – 88.11 Mb PubMed search [3] [4]
Wikidata
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Potassium channel, subfamily K, member 12, also known as KCNK12 is a human gene. The protein encoded by this gene, K_2P12.1, is a potassium channel containing two pore-forming P domains.^[5]

See also[edit]

• Tandem pore domain potassium channel

References[edit]

Further reading[edit]

External links[edit]

• KCNK12+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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