Contents

KCTD13

Protein-coding gene in the species Homo sapiens

KCTD13
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UIJ
Identifiers
Aliases	KCTD13, BACURD1, PDIP1, POLDIP1, hBACURD1, FKSG86, potassium channel tetramerization domain containing 13
External IDs	OMIM: 608947; MGI: 1923739; HomoloGene: 27800; GeneCards: KCTD13; OMA:KCTD13 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 29,905,012 bp[1] End 29,926,236 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 126,528,051 bp[2] End 126,544,803 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis nucleus accumbens anterior cingulate cortex right frontal lobe prefrontal cortex amygdala Region I of hippocampus proper caudate nucleus right hemisphere of cerebellum Top expressed in primary visual cortex superior frontal gyrus subiculum zygote dentate gyrus dentate gyrus of hippocampal formation granule cell piriform cortex globus pallidus cingulate gyrus hippocampus proper More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ubiquitin-protein transferase activity protein binding identical protein binding protein domain specific binding Cellular component Cul3-RING ubiquitin ligase complex nucleus nuclear body Biological process positive regulation of DNA replication DNA replication protein homooligomerization cell migration protein ubiquitination stress fiber assembly proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of Rho protein signal transduction positive regulation of synaptic transmission neural precursor cell proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 253980 233877 Ensembl ENSG00000174943 ENSMUSG00000030685 UniProt Q8WZ19 Q8BGV7 RefSeq (mRNA) NM_178863 NM_172747 RefSeq (protein) NP_849194 NP_766335 Location (UCSC) Chr 16: 29.91 – 29.93 Mb Chr 7: 126.53 – 126.54 Mb PubMed search [3] [4]
Wikidata
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BTB/POZ domain-containing protein KCTD13 is a protein that in humans is encoded by the KCTD13 gene.^[5][6]

Interactions[edit]

KCTD13 has been shown to interact with PCNA.^[5]

Clinical relevance[edit]

Mutations in this gene have been associated to abnormalities in brain growth and behaviour.^[7]

References[edit]

Further reading[edit]

External links[edit]

• PDBe-KB provides an overview of all the structure information available in the PDB for Human KCTD13

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.