In 2016, Lee began her career as a model and first acted in the music video entitled "Don't Leave" (Korean: 떠나지마) by Yang Da-il.[1] This prompted her desire to further act with dialogues, and so, debuted as an actress with the KBS2 television series My Fellow Citizens! (2019).[1][2]
In October 2020, Lee was selected as an endorsement model for South Korean make-up brand, Hince. A representative from the brand stated: "We believe the sensuous and sophisticated atmosphere of Lee Ju-myoung fits the image of the brand well. We look forward to the future activities."[2]
In September 2022, the global fashion brand Mango Tail selected Lee as the first Korean model. A brand official said, "Actress Lee Ju-myoung unique and fashionable charm and dignified attitude matched the image pursued by the brand, so I was selected as the first Korean model. I look forward to it."[3]
^ abSong Oh-jung (March 24, 2022). "김태리 노래 듣고 '끝났다' 생각"...이주명X최현욱, '2521' 비하인드(두데)[종합] [Lee Joo-myung X Choi Hyun-wook Share Behind the Scenes From '2521', "When I Heard Kim Tae-ri's Voice, I Thought 'It's Over'" (Dude) [General]]. Newsen (in Korean). Archived from the original on April 1, 2022. Retrieved March 31, 2022.
^ abcLee, Da-gyeom (October 30, 2020). "이주명, 가을 물들인 비주얼...'세련+우아美'" [Lee Joo-myung's Autumn-colored Visuals... 'Stylish + Elegance']. Star Today (in Korean). Archived from the original on April 24, 2021. Retrieved April 24, 2021.
^Kim Hyun-sook (September 21, 2022). "이주명, 글로벌 패션 브랜드 첫 한국 모델로 발탁...대세 입증" [Lee Joo-myung, the first Korean model for a global fashion brand... Proof of the trend] (in Korean). Newsis. Archived from the original on September 21, 2022. Retrieved September 21, 2022 – via Naver.
^Choi, Ji-ye (May 9, 2023). "이주명, 킬러 제압한 쉐도우...'패밀리' 특별출연" [Lee Joo-myung, the shadow who subdued the killer... Special appearance in 'Family'] (in Korean). Ten Asia. Archived from the original on May 9, 2023. Retrieved May 9, 2023 – via Naver.
^Kim Myung-mi (April 20, 2023). "모래에도 꽃이 핀다' 장동윤 이주명→윤종석 김보라 캐스팅[공식]" [Flowers Bloom Even in the Sand' Jang Dong-yoon Lee Joo-myung → Yoon Jong-suk Casting Kim Bo-ra [Official]] (in Korean). Newsen. Archived from the original on April 20, 2023. Retrieved April 20, 2023 – via Naver.
^Kim Hyun-sook (July 28, 2022). "볼륨을 높여요' 스페셜DJ박재정→이주명...내달 방송" ['Turn up the volume' special DJ Park Jae-jeong → Lee Joo-myeong... broadcast next month] (in Korean). Newsis. Archived from the original on July 28, 2022. Retrieved July 28, 2022 – via Naver.
^ abcBazar (March 24, 2022). <스물다섯 스물하나> 이주명, 의외의 과거?반전 매력! [Twenty-five Twenty-one's Lee Joo-myung, Unexpected Past? Reversal Charm!]. Harpers Bazar Korea (in Korean). Archived from the original on March 26, 2022. Retrieved March 26, 2022.
"With": "Billboard K-Pop 100". Billboard Korea. March 27 – April 2, 2022. Archived from the original on March 29, 2022. Retrieved March 30, 2022.
^Hong, Se-young (December 30, 2020). "[2020 MBC 연기대상] 안보현·김혜준 남녀 신인상" [[2020 MBC Drama Awards] Ahn Bo-Hyun·Kim Hye-Joon Male and Female Rookie Awards]. Sports Dongha (in Korean). Archived from the original on April 24, 2021. Retrieved April 24, 2021.