| |
| Names | |
|---|---|
| Preferred IUPAC name
2-Chloro-6-(piperazin-1-yl)pyrazine | |
| Other names
CPP | |
| Identifiers | |
3D model (JSmol) |
|
| ChemSpider | |
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C8H11ClN4 | |
| Molar mass | 198.65 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
MK-212 (CPPor6-chloro-2-(1-piperazinyl)pyrazine)[1] is a serotonin agonist.[2] It promotes the secretion of serum prolactin and cortisol in humans.[3]
In an experiment performed by Clineschidt and colleagues, they dosed mice with varying concentrations of MK-212, and observed its effects.[4] The result correlated very well to binding of indolealkylamine receptors, such as the serotonin and tryptamine receptors, which shows four characteristics. Namely, increased frequency of muscle twitching, increased twitching of the head,[5] "an increase in the strength of the crossed extensor reflex in the acutely spinalized rat", and the cause of complex motor syndrome.[4]
