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Names | |
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IUPAC name
1-[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-2-methoxypropan-1-one | |
Other names
Kenosin | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C18H25N5O4 | |
Molar mass | 375.429 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Metazosin is an antihypertensive α1-adrenergic receptor antagonist.[1][2]
The amide (3) is formed when piperazine is reacted with 2-methoxypropionylchloride (2). Metazosin is the product when this intermediate is reacted with the substituted quinazoline (4).[3][4]
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