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The Minister for Health is the Ghanaian government official responsible for the Ministry of Health.
| Number | Minister | Took office | Left office | Government | Party |
|---|---|---|---|---|---|
| 1 | J. H. Allassani (MP) | 6 March 1957 | July 1959 | Nkrumah government | Convention People's Party |
| 2 | Imoru Egala (MP)[1] | July 1959 | July 1960 | ||
| 3 | Lawrence Rosario Abavana (MP) | July 1960 | June 1961 | ||
| 4 | Komla Agbeli Gbedemah (MP) | June 1961 | |||
| 5 | Lawrence Rosario Abavana (MP) | October 1963 | January 1964 | ||
| 6 | Joseph Kodzo (MP) | December 1964 | June 1965 | ||
| 7 | Osei Owusu Afriyie (MP) | June 1965 | February 1966 | ||
| 8 | Eustace Akwei[2] | 1966 | 1969 | National Liberation Council | Military government |
| 9 | Gibson Dokyi Ampaw (MP) | 1969 | January 1971 | Busia government | Progress Party |
| 10 | Simon Diedong Dombo (MP) | January 1971 | January 1972 | ||
| 11 | Colonel J. C. Adjeitey | 1972 | 1973 | National Redemption Council | Military government |
| 12 | Lt. Colonel Anthony Hugh Selormey | May 1973 | October 1975 | ||
| 13 | Brigadier Odartey-Wellington[3][self-published source] | 1975 | ? | Supreme Military Council | |
| 14 | Abeifaa Karbo[4] | July 1977 | November 1978 | ||
| 15 | |||||
| 16 | Emmanuel Evans Anfom | June 1979 | September 1979 | Armed Forces Revolutionary Council | |
| 17 | Michael Paul Ansah (MP) | September 1979 | August 1981 | Limann government | People's National Party |
| 18 | Kwamena Ocran[5] | August 1981 | 31 December 1981 | ||
| 19 | Charles Buadu | 1983 | 1987 | Provisional National Defence Council | Military government |
| 20 | Air Commodore F. W. K. Klutse | 1987 | 1988 | ||
| 21 | Nana Akuoko Sarpong | 1988 | 1991 | ||
| 22 | Stephen Obimpeh | 1992 | 7 January 1993 | ||
| August 1994 | 1996 | Rawlings government | National Democratic Congress | ||
| 23 | Eunice Brookman-Amissah | 1996 | 1998 | ||
| 24 | Samuel Nuamah Donkor | 1998 | February 2000 | ||
| 25 | Kwame Danso-Boafo | February 2000[6] | 7 January 2001 | ||
| 26 | Richard Winfred Anane (MP) | 2001 | 2003 | Kufuor government | New Patriotic Party |
| 27 | Kwaku Afriyie | 2003 | 2005 | ||
| 28 | Courage Quashigah | 2005 | 7 January 2009 | ||
| 29 | George Sipa-Adjah Yankey | 2009 | 2009 | Mills government | National Democratic Congress |
| 30 | Benjamin Kunbuor (MP) | 2009 | 2011 | ||
| 31 | Joseph Yieleh Chireh (MP) | 2011 | 2012 | ||
| 32 | Alban Bagbin (MP) | 26 January 2012[7] | 24 July 2012 | ||
| 24 July 2012 | 7 January 2013 | Mahama government | |||
| 33 | Hanny-Sherry Ayitey[8][9] | 14 February 2013 | 16 July 2014 | ||
| 34 | Kwaku Agyemang-Mensah[10] | 16 July 2014 | 14 March 2015 | ||
| 35 | Alex Segbefia | 16 March 2015 | 6 January 2017 | ||
| 36 | Kwaku Agyemang-Manu (MP) | 28 January 2017[11] | incumbent | Akufo-Addo government | New Patriotic Party |
