Contents

NOXO1

Protein-coding gene in the species Homo sapiens

NOXO1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2L73
Identifiers
Aliases	NOXO1, P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28, NADPH oxidase organizer 1
External IDs	OMIM: 611256; MGI: 1919143; HomoloGene: 12418; GeneCards: NOXO1; OMA:NOXO1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 1,978,917 bp[1] End 1,984,192 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 A3.3|17 12.49 cM Start 24,915,208 bp[2] End 24,919,503 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon gonad testicle rectum appendix olfactory zone of nasal mucosa right hemisphere of cerebellum mucosa of sigmoid colon right lobe of liver left testis Top expressed in Paneth cell crypt of lieberkuhn of small intestine spermatocyte large intestine colon left colon ileum spermatid jejunum intestinal villus More reference expression data BioGPS n/a
Gene ontology Molecular function enzyme binding superoxide-generating NADPH oxidase activator activity protein binding phospholipid binding identical protein binding lipid binding phosphatidylinositol binding Cellular component plasma membrane NADPH oxidase complex membrane intracellular anatomical structure Biological process regulation of respiratory burst extracellular matrix disassembly positive regulation of catalytic activity regulation of hydrogen peroxide metabolic process superoxide metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 124056 71893 Ensembl ENSG00000196408 ENSMUSG00000019320 UniProt Q8NFA2 Q8VCM2 RefSeq (mRNA) NM_001267721 NM_144603 NM_172167 NM_172168 NM_027988 NM_001357836 RefSeq (protein) NP_001254650 NP_653204 NP_751907 NP_751908 NP_082264 NP_001344765 Location (UCSC) Chr 16: 1.98 – 1.98 Mb Chr 17: 24.92 – 24.92 Mb PubMed search [3] [4]
Wikidata
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NADPH oxidase organizer 1 is an enzyme that in humans is encoded by the NOXO1 gene.^[5]

References[edit]

Further reading[edit]

External links[edit]

• PDBe-KB provides an overview of all the structure information available in the PDB for Human NADPH oxidase organizer 1

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.