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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Perforating granuloma annulare (PGA ) is a skin condition of unknown cause, usually appearing on the dorsal hands, presenting as papules with a central keratotic core.[1] : 704
Signs and symptoms
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Perforating granuloma annulare is characterized by flesh-to-red, umbilicated papules or pustules that range in size from 1 to 5 mm.[2] papules are frequently arranged in an annular form and frequently have an exudate, crusting, or scaling covering them.[3] [4]
Causes
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The cause of perforating granuloma annulare is unknown.[3]
Diagnosis
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Granulomas containing histiocytes arranged in a palisading pattern surround necrobiotic collagen , which is usually represented by the deposition of mucin and infrequently fibrin , according to the histopathologic features of PGA.[3] epidermis is perforated and necrobiotic material is expelled as a result of the granulomas ' location in the superficial reticular dermis .[4]
Treatment
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Complete excision, psoralen and UVA therapy, intralesional triamcinolone , and high-dose corticosteroids are among the PGA treatment options.[2]
See also
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References
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^ a b c Alves, João; Barreiros, Hugo; Bártolo, Elvira (September 4, 2014). "Perforating Granuloma Annulare — An Unusual Subtype of a Common Disease" . Healthcare . 2 3 ). MDPI AG: 338–345. doi :10.3390/healthcare2030338 ISSN 2227-9032 . PMC 4934595 PMID 27429281 .
^ a b Witkoff, Benjamin M.; Ivanov, Nedyalko N.; Trotter, Shannon C. (August 6, 2019). "Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion" . Case Reports in Dermatology . 11 2 ). S. Karger AG: 233–238. doi :10.1159/000501875 . ISSN 1662-6567 . PMC 6738183 PMID 31543770 . (Retracted, see doi :10.1159/000519791 . If this is an intentional citation to a retracted paper, please replace {{retracted |...}} with {{retracted |...|intentional=yes}}. )
Further reading
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Lopez-Navarro, Norberto; Castillo, Rosa; Gallardo, MarÍa A.; Alcaide, Antonio; Matilla, Alfredo; Herrera, Enrique (January 1, 2008). "Successful treatment of perforating granuloma annulare with 0.1% tacrolimus ointment". Journal of Dermatological Treatment . 19 6 ). Informa UK Limited: 376–377. doi :10.1080/09546630802132650 . ISSN 0954-6634 . PMID 18608717 . S2CID 28009992 .
Peñas, Pablo F.; Jones-Caballero, María; Fraga, Javier; Sánchez-Pérez, Javier; García-Díez, Amaro (1997). "Perforating granuloma annulare". International Journal of Dermatology . 36 5 ). Wiley: 340–348. doi :10.1046/j.1365-4362.1997.00047.x . ISSN 0011-9059 . PMID 9199980 . S2CID 24831501 .
External links
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R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Perforating_granuloma_annulare&oldid=1233151007 " C a t e g o r y : ● M o n o c y t e - a n d m a c r o p h a g e - r e l a t e d c u t a n e o u s c o n d i t i o n s H i d d e n c a t e g o r i e s : ● A r t i c l e s c i t i n g r e t r a c t e d p u b l i c a t i o n s ● A r t i c l e s w i t h s h o r t d e s c r i p t i o n ● S h o r t d e s c r i p t i o n i s d i f f e r e n t f r o m W i k i d a t a
● T h i s p a g e w a s l a s t e d i t e d o n 7 J u l y 2 0 2 4 , a t 1 4 : 5 5 ( U T C ) . ● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n . ● P r i v a c y p o l i c y ● A b o u t W i k i p e d i a ● D i s c l a i m e r s ● C o n t a c t W i k i p e d i a ● C o d e o f C o n d u c t ● D e v e l o p e r s ● S t a t i s t i c s ● C o o k i e s t a t e m e n t ● M o b i l e v i e w
