Contents

Propamidine

Propamidine

Names
Preferred IUPAC name 4,4′-[Propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide)
Identifiers
CAS Number	104-32-5 Y 140-63-6 (isethionate) Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:87462 N
ChEMBL	ChEMBL23013 Y
ChemSpider	58475 Y
ECHA InfoCard	100.002.905
PubChem CID	64949
UNII	G20G12V769 Y 7T9IJ84C42 (isethionate) Y
CompTox Dashboard (EPA)	DTXSID6048674
InChI InChI=1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Y Key: WTFXJFJYEJZMFO-UHFFFAOYSA-N Y InChI=1/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21) Key: WTFXJFJYEJZMFO-UHFFFAOYAO
SMILES O(c1ccc(cc1)C(=[N@H])N)CCCOc2ccc(C(=[N@H])N)cc2
Properties
Chemical formula	C17H20N4O2
Molar mass	312.373 g·mol−1
Pharmacology
ATC code	D08AC03 (WHO) S01AX15 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Chemical compound

Propamidine is an antiseptic and disinfectant.

Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.^[1]

Propamidine is a member of the aromatic diamidine group of compounds which possess bacteriostatic properties against a wide range of organisms. These diamidines exert antibacterial action against pyrogenic cocci, antibiotic resistant staphylococci and some Gram-negative bacilli, the activity of the diamidines being retained in the presence of organic matter such as tissue fluids, pus and serum.^[2]

References[edit]

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