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Names | |
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Preferred IUPAC name
Diethyl quinolin-3-yl phosphate | |
Other names
3-(Diethoxyphosphinyloxy)-quinoline | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C13H16NO4P | |
Molar mass | 281.248 g·mol−1 |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
Highly toxic |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
1 mg/kg (mice, intravenous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.[1]
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