The following is a list of players, both past and current, who appeared at least in one game for the San Diego Padres National League franchise (1969–present).
Players in Bold are members of the National Baseball Hall of Fame.
Players in Italics have had their numbers retired by the team.
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| Franchise |
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| Ballparks |
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| Culture |
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| Lore |
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| Rivalries |
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| Key personnel |
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| League pennants (2) |
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| Division titles (5) |
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| Wild card berths (2) |
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| Minor league affiliates |
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| Broadcasting |
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