Talk:Herpes

Please cite source. I have seen exactly the opposite stated elsewhere.

(Raised again as an issue in June 2013. Need to find a source or delete it if none can be found. Lesion (talk) 02:53, 13 June 2013 (UTC))

In addition, please see the following meta-analysis: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jan;105(1):43-50. Epub 2007 Aug 20. Asymptomatic shedding of herpes simplex virus (HSV) in the oral cavity. Miller CS, Danaher RJ.

FOOTNOTE 89 seems to offer a partial list of support groups. Can Herpes Viruses Association be added too please? A Wikipage about this charity is about to go live.

TERMINOLOGY - since 'herpes' is the name of a family of 9 viruses, this page should refer to 'genital herpes' (or ano-genital herpes if you want total accuracy) or to 'herpes simplex' throughout.

A sentence in paragraph two reads, "After initial infection, the viruses move to sensory nerves, where they become latent and reside as life-long." Please remove commas and fix the nonsensical last bit, thanks!

Notes from peer review - March 2008

Quick mention to whoever keeps this updated - most texts and updated sources now call herpes as "human herpes virus-#" with the # being the subtype (HHV-1, HHV-2), HSV is an outdated term. Should the article be updated accordingly?

Just naming, all the info should be the same..

FACTS If you used someones lipstick or lipbalm once then you have a 99.99% chance you will NOT get oral herpes. But if you use it costently for example everyday for 2 or 3 weeks then your chances of not getting it are much lower. So do NOT be scared if you used someones lipstick once that you might get herpes.

• a few words explaining what a primary infection is would be pertinent at the first use (unless it is there and I missed it)
• I'd drop the whole Legal redress section. I feel it doesn't add anything useful to the article and, given the source of the references, it is likely not a world-wide position but is rather US-centric.

done ~ Ciar ~ _{(Talk to me!)} 02:27, 25 March 2008 (UTC)

Specific issues

From reading through a few random sections

• In the Disorders section the statement "...although recent years are seeing an increase in oral HSV-2 infections." is vague and dates fast. It's preferable to have something more concrete like "...although oral HSV-2 infection rates increased by <x>% in the last <y> years of the 20th Century".
• There is some redundancy - eg: in the Disorders section , including fever, and sore throat, and painful ulcers may appear - appears to say the same thing more concisely. Rare occasions of reinfections occur inside the mouth - again appears to say the same thing.

Fixed ~ Ciar ~ _{(Talk to me!)} 02:43, 25 March 2008 (UTC)

Oral herpes is spread by direct contact with an active sore in an infected person, for instance, during kissing -> Oral herpes is spread by direct contact with an infected person's active sores, for instance during kissing.

reworded ~ Ciar ~ _{(Talk to me!)} 02:47, 25 March 2008 (UTC)

• HSV-2 is the most common cause of recurrent viral meningitis called Mollaret's meningitis - should this have the words "a type of" inserted after "of" unless this is the only type of viral meningitis.

reworded ~ Ciar ~ _{(Talk to me!)} 02:54, 25 March 2008 (UTC)

• In the Bell's palsy section, first section needs a comma, possibly just after "nerves of the face".

added ~ Ciar ~ _{(Talk to me!)} 02:59, 25 March 2008 (UTC)

• The penultimate sentence and its predecessor in the "Orofacial infection" section) contradict each other. try Oral herpes is usually spread by direct contact
• In the "Natural compounds" section, However, there is currently insufficient scientific and clinical evidence "However" is not needed and "currently" adds nothing unless there is a date noting when this refers to. Please look for all uses of the word "currently" and rewrite to either remove the word or add a date/year.
• In the "Antiviral medication" section the sentence with by interfering with viral replication, effectively slowing the replication rate needs some work. It is unclear from the writing whether the drugs work by in effect slowing the replication or are effective at the slowing. If it's the "in effect" one then the word "effectively" can be removed.
• Same section. There are several prescription antiviral medications for controlling herpes simplex outbreaks.... Are they prescription drugs worldwide or just in the US ? Please check through the treatment section as many parts are written from a US perspective and need consideration as to whether the information is applicable worldwide.

- Peripitus (Talk) 11:50, 21 March 2008 (UTC)

There is a new drug under development that is currently not mentioned in the treatment section. Some information about it is as follows:

Another HSV-2 treatment undergoing phase II clinical trials is AIC316 from AiCuris GmbH & Co.KG. ^[1] Its mode of operation is different than existing treatments as it is a helicase-primase inhibitor. It can be used for episodic and suppressive treatment and is hailed as having resistance-breaking properties. This drug may also be effective against HSV-1 due to the similarity of the viral DNA. ^[2]

The CDC recommends against testing the general public/those without symptoms for herpes. www.cdc.gov/nchhstp/newsroom/hsv2pressrelease.html 90% of those with HSV are asymptomatic, or show little to no symptoms, yet they still spread the virus 20% of the time. Only 10% are aware that they carry the virus, as they are symptomatic, have been tested and have received a diagnosis. It can be concluded that 90% of those with herpes are unaware of their herpes infection. http://journals.lww.com/stdjournal/Fulltext/2004/05000/Seroprevalence_of_Herpes_Simplex_Virus_2_in.10.aspx Anamiatan (talk) 10:01, 31 March 2011 (UTC)