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Clinical data | |
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Trade names | Ceretec |
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Routes of administration | Intravenous |
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Chemical and physical data | |
Formula | C13H25N4O3Tc |
Molar mass | 383 g·mol−1 |
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Chirality | racemic |
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Technetium (99mTc) exametazime is a radiopharmaceutical sold under the trade name Ceretec, and is used by nuclear medicine physicians for the detection of altered regional cerebral perfusion in stroke[1] and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections[2] and inflammatory bowel disease.[3] Exametazime (the part without technetium) is sometimes referred to as hexamethylpropylene amine oximeorHMPAO, although correct chemical names are:[4]
The drug consists of exametazime as a chelating agent for the radioisotope technetium-99m. Both enantiomeric forms of exametazime are used—the drug is racemic.[5] The third stereoisomer of this structure, the meso form, is not included.
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