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Contents

   



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1 Title  





2 Content  





3 Reception  





4 Awards and honours  





5 Translations  





6 See also  





7 Notes and references  





8 Further reading  





9 External links  














The Emperor of All Maladies






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From Wikipedia, the free encyclopedia
 


The Emperor of All Maladies: A Biography of Cancer
Book cover; shows a crab in the center of the page, with the title above and the subtitle and author beneath
Cover of The Emperor of All Maladies
AuthorSiddhartha Mukherjee
LanguageEnglish
SubjectCancer
GenreNon-fiction
PublisherScribner

Publication date

16 November 2010
Publication placeUnited States
Pages592
ISBN978-1-4391-0795-9

The Emperor of All Maladies: A Biography of Cancer is a book written by Siddhartha Mukherjee, an Indian-born American physician and oncologist. It was published on 16 November 2010 by Scribner.

Title[edit]

The book explains its title in its author's note:[1]

In a sense, this is a military history—one in which the adversary is formless, timeless, and pervasive. Here, too, there are victories and losses, campaigns upon campaigns, heroes and hubris, survival and resilience—and inevitably, the wounded, the condemned, the forgotten, the dead. In the end, cancer truly emerges, as a nineteenth-century surgeon once wrote in a book's frontispiece, as "the emperor of all maladies, the king of terrors."

Content[edit]

The book weaves together Mukherjee's experiences as a hematology/oncology fellowatMassachusetts General Hospital as well as the history of cancer treatment and research.[2][3] Mukherjee gives the history of cancer from its first identification 4,600 years ago by the Egyptian physician Imhotep. The Greeks had no understanding of cells, but they were familiar with hydraulics. Hippocrates thus considered illness to be an imbalance of four cardinal fluids: blood, black bile, yellow bile, phlegm. Galen applied this idea to cancer, believing it to be an imbalance of black bile. In 440 BC, the Greek historian Herodotus recorded the first breast tumor excision of Atossa, the queen of Persia and the daughter of Cyrus, by a Greek slave named Democedes. The procedure was believed to have been successful temporarily. Galen's theory was later challenged by the work of Andreas Vaselius and Matthew Baille, whose dissections of human bodies failed to reveal black bile.

In the 19th century, surgeons devised various approaches to remove tumors, like William Halsted and the radical mastectomy. Additionally, Emil Grubbe used X-rays to treat cancer, thus identifying another treatment modality. Rudolph Virchow first observed leukemia, and Franz Ernst Christian Neumann localized the pathology to the bone marrow.

In the 20th century, cancer became the second most common cause of death after heart disease in the United States. Sidney Farber induced temporary remission in pediatric leukemia using antifolates developed by Yellapragada Subbarow. Louis Goodman and Alfred Gilman also used nitrogen mustard to treat lymphoma. The National Cancer Institute (NCI) introduced clinical trials to test the efficacy of chemotherapy. Recognizing the possibility for a cure, Farber sought funding for his efforts through The Jimmy Fund and Mary Lasker. Inspired by the Space Race, Farber and Lasker appealed to the nation and President Nixon to enact legislation for the War on Cancer, resulting in the passage of the National Cancer Act of 1971 and increased funding for the NCI.

The book also reviews the origins of hospice and palliative medicine and cancer screening.

According to Mukherjee, the book was a response to the demand of a patient: "I'm willing to go on fighting, but I need to know what it is that I'm battling."[4] Mukherjee states that two of his influences for the book were Randy Shilts' And the Band Played On and Richard Rhodes' The Making of the Atomic Bomb, but the defining moment for him was "when he conceived of his book as a biography".[4]

Reception[edit]

The Emperor of All Maladies won the 2011 Pulitzer Prize for General Non-Fiction: the jury called it "an elegant inquiry, at once clinical and personal".[5][6][2] The Guardian wrote that "Mukherjee manages to convey not only a forensically precise picture of what he sees, but a shiver too, of what he feels."[7] Literary Review commended Mukherjee's narrative: "It is so well written, and the science is so clearly explained, that it reads almost like a detective story—which, of course, it is."[8]

It was described, by the magazine TIME, as one of the 100 most influential books of the last 100 years,[9] and by The New York Times Magazine as among the 100 best works of non-fiction.[10]

Awards and honours[edit]

Translations[edit]

See also[edit]

Notes and references[edit]

  1. ^ Page xvii
  • ^ a b "An Oncologist Writes 'A Biography Of Cancer'". Fresh Air from WHYY. NPR. 17 November 2010. Retrieved 1 August 2011.
  • ^ Okie, Susan (28 November 2010). "Review: "The Emperor of All Maladies: A Biography of Cancer," by Siddhartha Mukherjee". Denver Post. Retrieved 29 September 2011.
  • ^ a b McGrath, Charles (8 November 2010). "How Cancer Acquired Its Own Biographer". The New York Times. Retrieved 22 December 2012.
  • ^ The Pulitzer Prizes. "The 2011 Pulitzer Prize Winners General Nonfiction". Retrieved 22 December 2012.
  • ^ "Indian doc's book on cancer wins Pulitzer Prize". The Times of India. Boston. 19 April 2011. Archived from the original on 5 November 2012. Retrieved 29 September 2011.
  • ^ "The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee—review". TheGuardian.com. 23 January 2011.
  • ^ Daniels, Anthony (March 2011). "The Unnameable". Literary Review.
  • ^ Cruz, Gilbert (17 August 2011). "All-TIME 100 Nonfiction Books". Time. Retrieved 16 December 2017.
  • ^ Lindgren, Hugo. "As if You Don't Have Enough to Read". The 6th Floor. The New York Times Magazine. Retrieved 16 December 2017.
  • ^ Joanna Bourke (10 October 2011). "2011 Wellcome Trust Book Prize shortlist". The Lancet. Retrieved 30 September 2012.
  • Further reading[edit]

    External links[edit]

  • icon Books

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=The_Emperor_of_All_Maladies&oldid=1217705844"

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