Transient neonatal diabetes | |
---|---|
Transient neonatal diabetes mellitus is inherited in an autosomal dominant manner[1] | |
Specialty | Pediatrics |
Transient neonatal diabetes mellitus (TNDM) is a form of neonatal diabetes presenting at birth that is not permanent. This disease is considered to be a type of maturity onset diabetes of the young (MODY).
Type | OMIM | Gene | Locus | Description |
---|---|---|---|---|
TNDM1 | 601410 | ZFP57, PLAGL1 | 6p22.1, 6q24.2 | |
TNDM2 | 610374 | ABCC8 | 11p15.1 | Due to the mutations of the other subunit of the KATP channel, SUR1, which is encoded by the ABCC8 gene.[2] |
TNDM3 | 610582 | KCNJ11 | 11p15.1 |
This condition has to do with genetics and is often associated with having an added Chromosome 7 gene (mostly from the paternal side).[citation needed]
The form on chromosome 6 can involve imprinting.[3][4]
This section is empty. You can help by adding to it. (September 2017)
|
This section is empty. You can help by adding to it. (September 2017)
|
| |
---|---|
Types |
|
Blood tests |
|
Management |
|
Complications |
|
Advocacy & Organizations |
|
Other |
|
Disorders due to genomic imprinting
| |||||
---|---|---|---|---|---|
Chromosome 6 |
| ||||
Chromosome 11 |
| ||||
Chromosome 15 |
| ||||
Chromosome 20 |
|
Genetic disorder, membrane: ABC transporter disorders
| |
---|---|
ABCA |
|
ABCB |
|
ABCC |
|
ABCD |
|
ABCG |
|
see also ABC transporters |
Genetic disorders relating to deficiencies of transcription factor or coregulators
| |||||||||
---|---|---|---|---|---|---|---|---|---|
(1) Basic domains |
| ||||||||
(2) Zinc finger DNA-binding domains |
| ||||||||
(3) Helix-turn-helix domains |
| ||||||||
(4) β-Scaffold factors with minor groove contacts |
| ||||||||
(0) Other transcription factors |
| ||||||||
Ungrouped |
| ||||||||
Transcription coregulators |
|
| |||||
---|---|---|---|---|---|
Calcium channel |
| ||||
Sodium channel |
| ||||
Potassium channel |
| ||||
Chloride channel |
| ||||
TRP channel |
| ||||
Connexin |
| ||||
Porin |
| ||||
See also: ion channels |