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P a g e s f o r l o g g e d o u t e d i t o r s l e a r n m o r e ● C o n t r i b u t i o n s ● T a l k
( T o p )
1 M e d i c a l u s e s
2 S i d e e f f e c t s
3 M e c h a n i s m o f a c t i o n
4 R e f e r e n c e s
5 E x t e r n a l l i n k s
T o g g l e t h e t a b l e o f c o n t e n t s
U r e a - c o n t a i n i n g c r e a m
5 l a n g u a g e s
● ا ل ع ر ب ي ة ● E s p a ñ o l ● Հ ա յ ե ր ե ն ● ଓ ଡ ଼ ି ଆ ● P o r t u g u ê s
E d i t l i n k s
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T o o l s
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● R e a d ● E d i t ● V i e w h i s t o r y
G e n e r a l
● W h a t l i n k s h e r e ● R e l a t e d c h a n g e s ● U p l o a d f i l e ● S p e c i a l p a g e s ● P e r m a n e n t l i n k ● P a g e i n f o r m a t i o n ● C i t e t h i s p a g e ● G e t s h o r t e n e d U R L ● D o w n l o a d Q R c o d e ● W i k i d a t a i t e m
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● D o w n l o a d a s P D F ● P r i n t a b l e v e r s i o n
A p p e a r a n c e
F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Urea , also known as carbamide-containing cream ,[clarification needed is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis , dermatitis , or ichthyosis .[1] [2] [3] nails .[3]
In adults side effects are generally few.[4] [1] [5] urea .[2] [3]
Urea containing creams have been used since the 1940s.[6] World Health Organization's List of Essential Medicines .[7] [8] over the counter .[3]
Medical uses [ edit ]
Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis , particularly where healing is inhibited by local skin infection , skin necrosis , fibrinous or itching debris or eschar .[5]
Side effects [ edit ]
Common side effects of urea cream are:
In severe cases, there can be an allergic reaction with symptoms such as skin rash , urticaria , difficulty breathing and swelling of the mouth, face, lips, or tongue.[9]
Mechanism of action [ edit ]
Urea in low doses is a humectant while at high doses (above 20%) it causes breakdown of protein in the skin.[10]
Urea dissolves the intercellular matrix of the cells of the stratum corneum , promoting desquamation of scaly skin , eventually resulting in softening of hyperkeratotic areas.[5] In nails , urea causes softening and eventually debridement of the nail plate.[5]
References [ edit ]
^ a b British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. pp. 796–798. ISBN 9780857111562
^ a b c d "Urea topical medical facts from Drugs.com" . www.drugs.com . Archived from the original on 18 January 2017. Retrieved 15 January 2017 .
^ Paradisis M, El Hachem M, Diociaiuti A, Giannetti A (2015). "Ichthyoses" . In Katsambas A, Lotti T, Dessinioti C, D'Erme AM (eds.). European Handbook of Dermatological Treatments (3rd ed.). Springer. p. 439. ISBN 9783662451397 Archived from the original on 2017-01-16.
^ a b c d e f g h i j k l m n "Urea Cream - FDA prescribing information, side effects and uses" . www.drugs.com . Archived from the original on 18 January 2017. Retrieved 15 January 2017 .
^ Harding CR, Bartolone J, Rawlings AV (1999). "Effects of natural moisturizing factor and lactic acid isomers on skin function." . In Loden M, Maibach HI (eds.). Dry Skin and Moisturizers: Chemistry and Function . CRC Press. p. 235. ISBN 9780849375200 Archived from the original on 2017-01-16.
^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019 . Geneva: World Health Organization. hdl :10665/325771 . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021) . Geneva: World Health Organization. hdl :10665/345533
^ a b c d e "Urea Cream (Consumer Information)" . Drugs.com . May 4, 2011. Archived from the original on 2011-02-26.
^ Sethi A, Kaur T, Malhotra SK, Gambhir ML (2016). "Moisturizers: The Slippery Road" . Indian Journal of Dermatology . 61 3 ): 279–287. doi :10.4103/0019-5154.182427 PMC 4885180 PMID 27293248 .
External links [ edit ]
"Urea" . Drug Information Portal . U.S. National Library of Medicine.
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Urea-containing_cream&oldid=1209611126 " C a t e g o r i e s : ● D e r m a t o l o g i c d r u g s ● U r e a s ● W o r l d H e a l t h O r g a n i z a t i o n e s s e n t i a l m e d i c i n e s H i d d e n c a t e g o r i e s : ● A r t i c l e s w i t h s h o r t d e s c r i p t i o n ● S h o r t d e s c r i p t i o n m a t c h e s W i k i d a t a ● C h e m i c a l s t h a t d o n o t h a v e a C h e m S p i d e r I D a s s i g n e d ● A r t i c l e s w i t h o u t E B I s o u r c e ● C h e m i c a l p a g e s w i t h o u t D r u g B a n k i d e n t i f i e r ● A r t i c l e s w i t h o u t K E G G s o u r c e ● A r t i c l e s w i t h o u t I n C h I s o u r c e ● A r t i c l e s c o n t a i n i n g u n v e r i f i e d c h e m i c a l i n f o b o x e s ● W i k i p e d i a a r t i c l e s n e e d i n g c l a r i f i c a t i o n f r o m N o v e m b e r 2 0 2 0 ● W i k i p e d i a m e d i c i n e a r t i c l e s r e a d y t o t r a n s l a t e
● T h i s p a g e w a s l a s t e d i t e d o n 2 2 F e b r u a r y 2 0 2 4 , a t 1 9 : 2 7 ( U T C ) . ● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n . ● P r i v a c y p o l i c y ● A b o u t W i k i p e d i a ● D i s c l a i m e r s ● C o n t a c t W i k i p e d i a ● C o d e o f C o n d u c t ● D e v e l o p e r s ● S t a t i s t i c s ● C o o k i e s t a t e m e n t ● M o b i l e v i e w
