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User:Mr. Ibrahem/Packed red blood cells

Mr. Ibrahem/Packed red blood cells

Bag of packed red blood cells.
Clinical data
Other names	Stored packed red blood cells, packed cells, red cell concentrate, red cell component
Routes of administration	IV

Packed red blood cells, also known as packed cells, are red blood cells that have been separated for blood transfusion.^[1] The packed cells are typically used in anemia that is either causing symptoms or when the hemoglobin is less than usually 70–80 g/L (7–8 g/dL).^[1][2][3] In adults, one unit brings up hemoglobin levels by about 10 g/L (1 g/dL).^[4][5] Repeated transfusions may be required in people receiving cancer chemotherapy or who have hemoglobin disorders.^[1] Cross matching is typically required before the blood is given.^[1] It is given by injection into a vein.^[6]

Side effects include allergic reactions such as anaphylaxis, red blood cell breakdown, infection, volume overload, and lung injury.^[1] With current preparation methods in the developed world the risk of viral infections such as hepatitis C and HIV/AIDS are less than one in a million.^[1] However, the risks of infection are higher in low income countries.^[7] Packed red blood cells are produced from whole blood or by apheresis.^[8] They typically last for three to six weeks.^[8]

The widespread use of packed red blood cells began in the 1960s.^[9] It is on the World Health Organization's List of Essential Medicines.^[10] In the United Kingdom they cost about £120 per unit.^[11] A number of other versions also exist including whole blood, leukocyte reduced red blood cells, and washed red blood cells.^[1]