Aminosteroids are a group of steroids with a similar structure based on an amino-substituted steroid nucleus.[1][2] They are neuromuscular blocking agents, acting as competitive antagonists of the nicotinic acetylcholine receptor (nAChR), and block the signalingofacetylcholine in the nervous system.[1][2][3] These drugs include candocuronium iodide (chandonium iodide), dacuronium bromide, dihydrochandonium, dipyrandium, malouetine, pancuronium bromide, pipecuronium bromide, rapacuronium bromide, rocuronium bromide, stercuronium iodide, and vecuronium bromide.[2][4]
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| nAChRsTooltip Nicotinic acetylcholine receptors |
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