Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | HLA-DR beta |
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Apolizumab is a humanized monoclonal antibody intended for use in hematologic cancers.[1][2] Development was abandoned in 2005, because of toxic effects and lack of efficacy in humans. The observed dose limiting toxic effects were aseptic meningitis and hemolytic uremia.[3]
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