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Tabalumab






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Tabalumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetBAFF
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6518H10008N1724O2032S38
Molar mass146252.08 g·mol−1
 ☒NcheckY (what is this?)  (verify)

Tabalumab (LY 2127399) is an anti-B-cell activating factor (BAFF) human monoclonal antibody designed for the treatment of autoimmune diseases and B cell malignancies.[1][2] Tabalumab was developed by Eli Lilly and Company.

A phase III clinical trial for rheumatoid arthritis was halted in Feb 2013.[3] In September 2014, a second phase III trial focussing on treating systemic lupus erythematosus, was terminated early as the study failed to meet its primary endpoint.[4]

References

[edit]
  1. ^ "Statement On A Nonproprietary Name Adopted By The USAN Council: Tabalumab" (PDF). American Medical Association.
  • ^ "BAFF Antibody: Tabalumab, LY2127399". Lilly USA, LLC. Archived from the original on 12 August 2013.
  • ^ "Press Release Archive - Press Release Archives".
  • ^ "Lilly Halts Tabalumab Development for Lupus". 2 October 2014.
  • Now dropped by Lilly due to lack of efficacy.


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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Tabalumab&oldid=1190944918"

    Categories: 
    Drugs not assigned an ATC code
    Drugs developed by Eli Lilly and Company
    Monoclonal antibody stubs
    Antineoplastic and immunomodulating drug stubs
    Hidden categories: 
    Articles with short description
    Short description is different from Wikidata
    Articles with changed CASNo identifier
    Chemicals that do not have a ChemSpider ID assigned
    Articles without EBI source
    Chemical pages without DrugBank identifier
    Articles without InChI source
    Drugs with no legal status
    Drugboxes which contain changes to verified fields
    Drugboxes which contain changes to watched fields
    Drugs that are a monoclonal antibody
    All stub articles
     



    This page was last edited on 20 December 2023, at 19:34 (UTC).

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