Contents

Betahydroxythiofentanyl

Opioid analgesic drug

Betahydroxythiofentanyl

Clinical data
Other names	β-hydroxythiofentanyl
ATC code	none
Legal status
Legal status	CA: Schedule I UK: Class A US: Schedule I
Identifiers
IUPAC name N-{1-[2-Hydroxy-2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide
CAS Number	1474-34-6
PubChem CID	62278
ChemSpider	21106268 Y
UNII	MG6JW60TUG
CompTox Dashboard (EPA)	DTXSID101014172
Chemical and physical data
Formula	C20H26N2O2S
Molar mass	358.50 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(=O)N(c1ccccc1)C2CCN(CC2)CC(c3cccs3)O
InChI InChI=1S/C20H26N2O2S/c1-2-20(24)22(16-7-4-3-5-8-16)17-10-12-21(13-11-17)15-18(23)19-9-6-14-25-19/h3-9,14,17-18,23H,2,10-13,15H2,1H3 Y Key:GLAAETOTOUGGSB-UHFFFAOYSA-N Y
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Betahydroxythiofentanyl (β-hydroxythiofentanyl) is an opioid analgesic that is an analogoffentanyl.

Betahydroxythiofentanyl was sold briefly on the black market from around 1985,^[1] before the introduction of the Federal Analog Act in 1986 which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared.^[2] β-hydroxythiofentanyl was anecdotally said to be one of the more favored fentanyl analogs by opiate addicts^{[citation needed]}.

Betahydroxythiofentanyl has effects and side effects similar to fentanyl. Side effects of fentanyl analogs include itching, nausea and potentially serious respiratory depression, which can be life-threatening.^{[citation needed]}

As of October 2015, betahydroxythiofentanyl is a controlled substance in China.^[3]

As of May 2016, betahydroxythiofentanyl was temporarily listed as a Schedule I controlled substance in the United States.^[4] A final ruling placing it in Schedule I was issued by the DEA on May 8, 2019 after a 1 year notice of proposed permanent scheduling.^[5] There were no petitions for hearings on the matter.^[6][7]

• Sufentanil
• Thiafentanil