Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system. C1s is part of the C1 complex.[5][6][7][8] In humans, it is encoded by the C1S gene.[9]
C1s cleaves C4 and C2, which eventually leads to the production of the classical pathway C3-convertase.
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PDB gallery
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1elv: CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COMPLEMENT C1S PROTEASE
1nzi: Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s
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| Digestive enzymes |
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| Venombin |
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