Contents

Cefsulodin

Chemical compound

Cefsulodin

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01DD03 (WHO)
Identifiers
IUPAC name 4-(aminocarbonyl)-1-[((6R,7R)-2-carboxy-8-oxo-7-{[phenyl(sulfo)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl]pyridinium
CAS Number	62587-73-9 Y Sodium salt: 52152-93-9 Y
PubChem CID	5284530
ChemSpider	4447588 Y
UNII	OV42LHE42B Sodium salt: 2D087186PY Y
KEGG	D02005 Y
ChEMBL	ChEMBL1617285 N
CompTox Dashboard (EPA)	DTXSID6022769
Chemical and physical data
Formula	C22H21N4O8S2+
Molar mass	533.55 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(c3ccccc3)S(=O)(=O)O)C[n+]4ccc(C(=O)N)cc4)C([O-])=O
InChI InChI=1S/C22H20N4O8S2/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34)/t15-,17?,21-/m1/s1 Y Key:SYLKGLMBLAAGSC-IKZMBGHXSA-N Y
NY (what is this?)  (verify)

Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by Takeda Pharmaceutical Company in 1977.^[1][2][3][4]

TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985.^[5]

Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms.^[6] This agar is most often used in water and beverage testing.^{[citation needed]}

The following represents MIC susceptibility data for various P. aeruginosa strains:^[7]

• Pseudomonas aeruginosa PA13 (resistant strain): 32 μg/ml
• Pseudomonas aeruginosa (wild-type, susceptible): 4 - 8 μg/ml