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Clinical data | |
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Trade names | Celospor, Celtol, Cristacef |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Intravenous, intramuscular, intramammary |
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Pharmacokinetic data | |
Protein binding | 23 to 38% |
Elimination half-life | 1.2 hours |
Excretion | Renal (72%) |
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ECHA InfoCard | 100.030.449 ![]() |
Chemical and physical data | |
Formula | C13H13N3O6S |
Molar mass | 339.32 g·mol−1 |
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Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections. It is a bacteriostatic antibiotic.[1][2] Cefacetrile is marketed under the trade names Celospor, Celtol, and Cristacef,[3] and as Vetimast for the treatment of mammary infections in lactating cows.[2]
It was made by reacting 7-ACA (7-aminocephalosporanic acid) with cyanoacetyl chloride in the presence of tributylamine.[citation needed]
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