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Deoxyguanosine triphosphate

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Deoxyguanosine triphosphate
Names


IUPAC name 2′-Deoxyguanosine 5′-(tetrahydrogen triphosphate)
Systematic IUPAC name O¹-{[(2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate
Identifiers
CAS Number	2564-35-4^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16497^N
ChEMBL	ChEMBL477486^N
ChemSpider	58613^Y
ECHA InfoCard	100.018.080
PubChem CID	65103
UNII	8C2O37Y44Q^Y
CompTox Dashboard (EPA)	DTXSID60948499 DTXSID50917119, DTXSID60948499
InChI InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1^Y Key: HAAZLUGHYHWQIW-KVQBGUIXSA-N^Y
SMILES O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n1cnc2c1NC(=N/C2=O)\N)C[C@@H]3O
Properties
Chemical formula	C₁₀H₁₆N₅O₁₃P₃
Molar mass	507.181023
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Deoxyguanosine triphosphate^[1] (dGTP) is a nucleoside triphosphate, and a nucleotide precursor used in cells for DNA synthesis. The substance is used in the polymerase chain reaction technique, in sequencing, and in cloning. It is also the competitor of inhibition onset by acyclovir in the treatment of HSV virus.^[2]

References[edit]

^ Nelson, David L.; Cox, Michael M. (2005). Principles of Biochemistry (4th ed.). New York: W. H. Freeman. ISBN 0-7167-4339-6.

^ Furman PA, Lambe CU, Nelson DJ (July 1982). "Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1". Am. J. Med. 73 (1A): 14–7. doi:10.1016/0002-9343(82)90056-0. PMID 6285704.

Nucleic acid constituents

Nucleotide
(Nucleoside monophosphate)

Ribonucleotide

Deoxyribonucleotide

Cyclic nucleotide

Nucleoside diphosphate

Nucleoside triphosphate

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Retrieved from "https://en.wikipedia.org/w/index.php?title=Deoxyguanosine_triphosphate&oldid=1152518949" Categories: ●Nucleotides ●Phosphate esters ●Organic compound stubs Hidden categories: ●Articles without InChI source ●Articles without KEGG source ●Articles with changed EBI identifier ●ECHA InfoCard ID from Wikidata ●Articles containing unverified chemical infoboxes ●Chembox image size set ●Articles with short description ●Short description matches Wikidata ●All stub articles ●This page was last edited on 30 April 2023, at 18:42 (UTC). ●Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. ●Privacy policy ●About Wikipedia ●Disclaimers ●Contact Wikipedia ●Code of Conduct ●Developers ●Statistics ●Cookie statement ●Mobile view