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Contents

   



(Top)
  


1 Veterinary uses  




2 References  













Fluocinonide






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From Wikipedia, the free encyclopedia
  

"Vanos" redirects here. Not to be confused with VANOSorVanossGaming.

Fluocinonide
Clinical data
Trade namesFluonex, Lidex, others[1]
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa601054
Routes of
administration		Topical
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: WARNING[2]Rx-only
    • Pharmacokinetic data
    MetabolismLiver
    Identifiers

    • 6α,9-difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone,21-acetate

    CAS Number
    PubChem CID
    IUPHAR/BPS
    DrugBank
    ChemSpider
    UNII
    KEGG
    ChEMBL
    CompTox Dashboard (EPA)
    ECHA InfoCard100.005.998 Edit this at Wikidata
    Chemical and physical data
    FormulaC26H32F2O7
    Molar mass494.532 g·mol−1
    3D model (JSmol)

    • O=C(OCC(=O)[C@]45OC(O[C@@H]5C[C@@H]2[C@@]4(C[C@H](O)[C@]3(F)[C@]/1(/C=C\C(=O)\C=C\1[C@@H](F)C[C@@H]23)C)C)(C)C)C

    • InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1 checkY

    • Key:WJOHZNCJWYWUJD-IUGZLZTKSA-N checkY

      (verify)

    Fluocinonide is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis.[3] It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort.[3]

    A common potential adverse effect is skin atrophy (thinning of the skin).[4]

    In 2021, it was the 249th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[5][6]

    Veterinary uses[edit]

    Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs.[7] Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure.[8]

    References[edit]

    1. ^ "Fluocinonide Topical". MedlinePlus Drug Information. U.S. National Library of Medicine.
  • ^ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
  • ^ a b "Fluocinonide Topical: MedlinePlus Drug Information". medlineplus.gov. Retrieved 16 November 2022.
  • ^ Jablonska S, Groniowska M, Dabroswki J (February 1979). "Comparative evaluation of skin atrophy in man induced by topical corticoids". The British Journal of Dermatology. 100 (2): 193–206. doi:10.1111/j.1365-2133.1979.tb05561.x. PMID 154921. S2CID 30656827.
  • ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
  • ^ "Fluocinonide - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
  • ^ Dog Allergies. Squidoo (Report).
  • ^ Zenoble RD, Kemppainen RJ (September 1987). "Adrenocortical suppression by topically applied corticosteroids in healthy dogs". Journal of the American Veterinary Medical Association. 191 (6): 685–688. PMID 2824410.

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Fluocinonide&oldid=1199180312"
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     ●Acetonides
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