Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene.[5][6][7]
Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002).[supplied by OMIM][7]
HDAC10 has been shown to interact with Histone deacetylase 2[8] and Nuclear receptor co-repressor 2.[8]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Hydrolases: carbon-nitrogen non-peptide (EC 3.5)
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3.5.1: Linear amides / Amidohydrolases |
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3.5.2: Cyclic amides/ Amidohydrolases |
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3.5.3: Linear amidines/ Ureohydrolases |
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3.5.4: Cyclic amidines/ Aminohydrolases |
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3.5.5: Nitriles/ Aminohydrolases |
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3.5.99: Other |
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Activity |
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Regulation |
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Classification |
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Kinetics |
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Types |
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