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(Top) 1 References

MRGPRG

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MRGPRG

Identifiers

MRGPRG, GPR169, MRGG, MAS related GPR family member G

External IDs

OMIM: 607234; MGI: 3033145; HomoloGene: 28580; GeneCards: MRGPRG; OMA:MRGPRG - orthologs

Gene location (Human)

Chromosome 11 (human)^[1]

11p15.4

Start

3,217,944 bp^[1]

End

3,218,813 bp^[1]

Gene location (Mouse)

Chromosome 7 (mouse)^[2]

7|7 F5

Start

143,317,447 bp^[2]

End

143,320,730 bp^[2]

RNA expression pattern

Mouse (ortholog)

Top expressed in

testicle

left testis

right testis

canal of the cervix

Top expressed in

decidua

white adipose tissue

muscle of thigh

olfactory epithelium

zone of skin

aorta

thymus

skeletal muscle tissue

uterus

esophagus

More reference expression data

n/a

Molecular function

signal transducer activity

G protein-coupled receptor activity

Cellular component

integral component of membrane

plasma membrane

integral component of plasma membrane

Biological process

G protein-coupled receptor signaling pathway

signal transduction

Sources:Amigo / QuickGO

Species

Human

Mouse

ENSG00000182170

ENSMUSG00000050276

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 11: 3.22 – 3.22 Mb

Chr 7: 143.32 – 143.32 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Mas-related G-protein coupled receptor member G (MRGG) also known as G-protein coupled receptor 169 (GPR169) is a protein that in humans is encoded by the MRGPRG gene. MRGG is an orphan G-protein coupled receptor.^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182170 – Ensembl, May 2017

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050276 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (April 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.

Cell surface receptor: G protein-coupled receptors

Class A: Rhodopsin-like

Neurotransmitter

α1 (A

B

D)

B

C)

Adenosine (A1

A3)

2

4

5

6

8

9

14)

(all but 5-HT3) 5-HT1 (A

B

D

E

F)

B

C)

5-HT (4

6

7)

Other

Acetylcholine (M1

M5)

D1
D2
D3
D4
D5

H1
H2
H3
H4

1C)

2

5

6

8

9)

Metabolites and
signaling molecules

CysLT (1

2)

1

2

DP (1
2), EP (1
2
3
4), FP

Other

Bile acid

Cannabinoid (CB1

CB2, GPR (18

119))

Free fatty acid (1

2

3

4)

Hydroxycarboxylic acids

1
2
3

Lysophosphatidic acid (1

2

3

4

5

6)

Lysophospholipid (1

2

3

4

5

6

7

8)

Sphingosine-1-phosphate (1

2

3

4

5)

Peptide

B/W (1

2)

FF (1

2)

S

Y (1

2

4

5)

Neuromedin (B

U (1

2))

2)

Other

Anaphylatoxin (C3a

C5a (1

2))

2)

Cholecystokinin (A

B)

A
B

Formyl peptide (1

2

3)

2

3)

Gonadotropin-releasing hormone (1

2)

Luteinizing hormone/choriogonadotropin

D

E

F

G

X4)

Melanocortin (1

2

3

4

5)

2)

Nociceptin & Zeta, but not Sigma)

2)

Prokineticin (1

2)

Prolactin-releasing peptide

2

3

4)

Somatostatin (1

2

3

4

5)

2

3)

Thyrotropin-releasing hormone

Vasopressin (1A

2)

Miscellaneous

Taste, bitter

TAS2R
- 1

3

4

5

7

8

9

Vomeronasal receptor type 1

GPR (1

3

4

6

Other

Adrenomedullin

4

5

Protease-activated (1

2

3

4)

2

3)

Class B: Secretin-like

ADGRB
- Brain-specific angiogenesis inhibitor
  - 1

2

3

ADGRC

Cadherin
- 1
- 2
- 3

ADGRE

EMR
- 1
- 2
- 3
CD97

ADGRG

1
2
3
4
5
6
7

ADGRL

Latrophilin
- 1
- 2
- 3
ELTD1

GPR (56

Other

Calcitonin

Corticotropin-releasing hormone (1

2)

Growth-hormone-releasing hormone

Methuselah-like proteins

Parathyroid hormone (1

2)

Vasoactive intestinal peptide (1

2)

Class C: Metabotropic glutamate / pheromone

Taste, sweet

TAS1R
- 1

2

3

Vomeronasal receptor, type 2

Other

Calcium-sensing receptor

2)

Glutamate receptor (Metabotropic glutamate (1

2

3

4

5

6

7

8))

2

3

4)

Class F: Frizzled & Smoothened

Frizzled

Frizzled (1

2

3

4

5

6

7

8

9

10)

Smoothened

Smoothened

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