FZD10
Identifiers
FZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10
External IDs
OMIM: 606147; MGI: 2136761; HomoloGene: 21411; GeneCards: FZD10; OMA:FZD10 - orthologs
Gene location (Human)
12q24.33
Start
End
Gene location (Mouse)
Chromosome 5 (mouse)[2]
5|5 G1.3
Start
End
Molecular function
Cellular component
Biological process
Mouse
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search
Frizzled-10 (Fz-10) is a protein that in humans is encoded by the FZD10 gene.[5][6] Fz-10 has also been designated as CD350 (cluster of differentiation 350).
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[6]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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signaling molecules
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Peptide
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Miscellaneous
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